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Publications

Our research is regularly featured in leading scientific journals across the fields of metabolism, pharmacology, cannabinoid science, and translational medicine. These publications reflect our lab’s commitment to advancing fundamental knowledge and developing innovative therapeutic strategies with real-world impact.

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Sleeve Gastrectomy Suppresses Hepatic Glucose Production and Increases Hepatic Insulin Clearance Independent of Weight Loss

Ben-Haroush Schyr R, Al-Kurd A, Moalem B, Permyakova A, Israeli H, Bardugo A, Hefetz L, Bergel M, Haran, A, Azar S, Magenheim I, Tam J, Grinbaum R, Ben-Zvi D

Diabetes 70(10): 2289-2298.
2021
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Counteracting Age-related VEGF Signaling Insufficiency Promotes Healthy Aging and Extends Lifespan

Grunewald M, Kumar S, Sharife H, Volinski E, Gileles-Hillel A, Licht T, Permyakova A, Maimon D, Hinden L, Azar S, Friedman Y, Tsuberi R, Oliven T, Anisimov A, Alitalo K, Horwitz M, Leebhoff S, Khoma OZ, Hlushchuk R, Djonov V, Abramovitch R, Tam J, Keshet E

Science 373, eabc8479
2021
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A Proposed Modulatory Role of the Endocannabinoid System on Adipose Tissue Metabolism and Appetite in Periparturient Dairy Cows

Myers MN, Zachut M, Tam J, Contreras AG

J Animal Sci Biotechnol 12, 21.
2021
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Endocannabinoid Levels in Ulcerative Colitis Patients Correlate with Clinical Parameters and are Affected by Cannabis Consumption

Tartakover Matalon S, Azar S, Meiri D, Hadar R, Nemirovski A, Abu Jabal N, Konikoff FM, Drucker L, Tam J, Naftali T

Frontiers in Endocrinology 12:685289.
2021
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Agonist of RORA Attenuates Non-Alcoholic Fatty Liver Progression in Mice via Upregulation of microRNA 122

Chai C, Cox B, Yaish D, Gross D, Rosenberg N, Amblard F, Shemuelian Z, Gefen M, Korach A, Tirosh O, Lanton T, Link H, Tam J, Permikova A, Ozhan G, Citrin J, Liao H, Tannous M, Hahn M, Axelrod J, Arretxe E, Alonso C, Martinez-Arranz I, Betés PO, Safadi R, Salhab A, Amer J, Tber Z, Mengshetti S, Giladi H, Schinazi RF, Galun E

Gastroenterology 159(3): 999-1014.e9
2020
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CB1R Regulates Soluble Leptin Receptor Levels via CHOP, Contributing to Hepatic Leptin Resistance

Drori A, Gammal A, Azar S, Hinden L, Hadar R, Wesley D, Nemirovski A, Szanda G, Salton M, Tirosh B, Tam J

eLife 9:e60771
2020

Featured in eLife Digest

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Dual Inhibition of Cannabinoid-1 Receptor and iNOS Attenuates Obesity-induced Chronic Kidney Disease

Udi S, Hinden L, Ahmad M, Drori A, Iyer MR, Cinar R, Herman-Edelstein M, Tam J

Br J Pharmacol 177(1):110-127.
2020
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Reversal of Diet-induced Hepatic Steatosis by Peripheral CB1 Receptor Blockade in Mice is p53/miRNA-22/SIRT1/PPARα Dependent

Azar S, Udi S, Drori A, Hadar R, Nemirovski A, Vemuri KV, Miller M, Sherill-Rofe D, Arad, Y, Gur-Wahnon D, Li X, Makriyannis A, Ben-Zvi D, Tabach Y, Ben-Dov IZ, Tam J

Mol Metab 42:101087
2020
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Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors

Kogot-Levin A, Hinden L, Riahi Y, Israeli T, Tirosh B, Cerasi E, Mizrachi EB, Tam J, Mosenzon O, Leibowitz G

Cell Reports 32(4): 107954
2020
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A Novel Indoline Derivative Ameliorates Diabesity-Induced Chronic Kidney Disease by Reducing Metabolic Abnormalities

Permyakova A, Gammal A, Hinden L, Weitman M, Weinstock M, Tam J

Frontiers in Endocrinology 11:91
2020

NO RESULTS

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