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Publications

Our research is regularly featured in leading scientific journals across the fields of metabolism, pharmacology, cannabinoid science, and translational medicine. These publications reflect our lab’s commitment to advancing fundamental knowledge and developing innovative therapeutic strategies with real-world impact.

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Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans

Wreven E, Ruiz de Adana MS, Gmyr V, Kerr-Conte J, Vallejo Herrera MJ, Hinden L, Benavides Espínola IC, Gómez Duro M, Salido LS, Bermúdez-Silva FJ, Linares F, Tam J, Egan JM, Olveira G, Pattou F, González-Mariscal I

Diabetologia
2024
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Lipolysis pathways modulate lipid mediator release and endocannabinoid system signaling in dairy cows’ adipocytes

Myers MN, Chirivi1 M, Gandy JC, Tam J, Zachut M, Contreras AG

Journal of Animal Science and Biotechnology, 15, 103.
2024
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Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3

Szanda G, Jourdan T, Wisniewski E, Cinar R, Godlewski G, Rajki A, Liu J, Chedester L, Szalai B, Tóth AD, Soltész-Katona E, Hunyady L, Inoue A, Horváth VB, Spät A, Tam J, Kunos G

iScience 12;27(2):108802.
2023
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Cannabinoid-1 Receptor Activation Modulates Lipid Mobilization and Adipogenesis in the Adipose Tissue of Dairy Cows

Myers M, Abou-Rjeileh U, Chirivi M, Parales J, Lock A, Tam J, Zachut M, Contreras A

J Dairy Sci 106:3650-3661.
2023
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Kidney Proximal Tubule GLUT2—More than Meets the Eye

Ahmad M, Abramovich I, Agranovich B, Nemirovski A, Gottlieb E, Hinden L, Tam J

Cells 12, 94.
2023
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Hepatic Targeting of the Centrally Active Cannabinoid 1 Receptor (CB1R) Blocker Rimonabant via PLGA Nanoparticles for Treating Fatty Liver Disease and Diabetes

Hirsch S, Hinden L, Naim-Ben-David M, Baraghithy S, Permyakova A, Azar S, Nasser T, Portnoy E, Agbaria M, Nemirovski A, Golomb G, Tam J

J Control Release 353:254-269.
2023
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Lysine tRNA fragments and miR-194-5p co-regulate hepatic steatosis via β-Klotho and perilipin 2

Tzur Y, Winek K, Madrer N, Dubnov S, Bennett ER, Greenberg DS, Hanin G, Gammal A, Tam J, Arkin IT, Paldor I, Soreq H

Mol Metab 101856.
2023
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Alpha-linolenic Acid Modulates Systemic and Adipose Tissue-specific Insulin Sensitivity, Inflammation, and the Endocannabinoid System in Dairy Cows

Kra G, Daddam, JR, Moallem U, Kamer H, Muallem B, Levin Y, Kočvarová R, Nemirovski A, Contreras AJ, Tam J, Zachut M

Sci Rep 13:5280.
2023
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Systemic Changes in Endocannabinoids and Endocannabinoid-like Molecules in Response to Partial Nephrectomy-Induced Ischemia

Rothner A, Gov T, Hinden L, Nemirovski A, Tam J, Rosenzweig B

Int J Mol Sci, 24, 4216.
2023
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Mapping the Metabolic Reprogramming Induced by Sodium-Glucose Cotransporter 2 Inhibition

Kogot-Levin A, Riahi Y, Abramovich I, Mosenzon O, Agranovich B, Kadosh L, Ben-Haroush Schyr R, Kleiman D, Hinden L, Cerasi E, Ben-Zvi D, Bernal Mizrachi E, Tam J, Gottlieb E, Leibowitz G

JCI Insight 10;8(7):e164296.
2023

NO RESULTS

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