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Publications

Our research is regularly featured in leading scientific journals across the fields of metabolism, pharmacology, cannabinoid science, and translational medicine. These publications reflect our lab’s commitment to advancing fundamental knowledge and developing innovative therapeutic strategies with real-world impact.

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FucoVital® inhibits fatty acid accumulation in liver cells in vitro and
reduces triglycerides levels in patients with NAFLD

Bermont A, Cohen DL, Richter V, Hadar R, Tam J, Wandel A, Brawer S, Grundman O, Shirin H

PharmaNutrition, 31, 100429
2025
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Characterization of metabolic alterations in the lean metabolically unhealthy alpha defensin transgenic mice

Higazi AA, Maraga E, Baraghithy S, Udi S, Azar S, Saada A, Glaser B, Avrahami D, Abdeen S, Hamdan Z, Tam J, Abu Fanne R

iScience, 27(2): 108802.
2024
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The Autophagic Activator GHF-201 Can Alleviate Pathology in a Mouse Model and in Patient Fibroblasts of Type III Glycogenosis

Mishra K, Sweetat S, Baraghithy S, Sprecher U, Marisat M, Bastu S, Glickstein H, Tam J, Rosenmann H, Weil M, Malfatti E, Kakhlon O

Biomolecules, 14(8):893
2024
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5-Methoxy-2-aminoindane Reverses Diet-Induced Obesity and Improves Metabolic Parameters in Mice: A Potential New Class of Antiobesity Therapeutics

Baraghithy S, Gammal A, Permyakova A, Hamad S, Kočvarová R, Calles Y and Tam J

ACS Pharmacol. Transl. Sci. 2024, 7, 8, 2527–2543
2024

Appeared on the August 2024 Supplemental Cover Page of ACS Pharmacol Transl Sci

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Renal Mitochondrial ATP Transporter Ablation Ameliorates Obesity-Induced Chronic Kidney Disease

Permyakova A, Hamad S, Hinden L, Baraghithy S, Kogot-Levin A, Yosef O, Shalev O, Tripathi MK, Amal H, Basu A, Arif M, Cinar R, Kunos G, Berger M, Leibowitz G, Tam J

Journal of the American Society of Nephrology
2024

Appeared on the March 2024 cover page of J Am Soc Nephrol

Featured in J Am Soc Nephrol 1;35(3):257-258, 2024.

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Inhibition of somatostatin enhances the long-term metabolic outcomes of sleeve gastrectomy in mice

Kleiman D, Arad Y, Azulai S, Baker A, Bergel M, Elad A, Hefetz L, Israeli H, Littor M, Permyakova A, Samuel I, Tam J, Ben-Haroush Schyr R, Ben-Zvi D

Molecular Metabolism, 86:101979.
2024
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Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans

Wreven E, Ruiz de Adana MS, Gmyr V, Kerr-Conte J, Vallejo Herrera MJ, Hinden L, Benavides Espínola IC, Gómez Duro M, Salido LS, Bermúdez-Silva FJ, Linares F, Tam J, Egan JM, Olveira G, Pattou F, González-Mariscal I

Diabetologia
2024
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Lipolysis pathways modulate lipid mediator release and endocannabinoid system signaling in dairy cows’ adipocytes

Myers MN, Chirivi1 M, Gandy JC, Tam J, Zachut M, Contreras AG

Journal of Animal Science and Biotechnology, 15, 103.
2024
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Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3

Szanda G, Jourdan T, Wisniewski E, Cinar R, Godlewski G, Rajki A, Liu J, Chedester L, Szalai B, Tóth AD, Soltész-Katona E, Hunyady L, Inoue A, Horváth VB, Spät A, Tam J, Kunos G

iScience 12;27(2):108802.
2023
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Cannabinoid-1 Receptor Activation Modulates Lipid Mobilization and Adipogenesis in the Adipose Tissue of Dairy Cows

Myers M, Abou-Rjeileh U, Chirivi M, Parales J, Lock A, Tam J, Zachut M, Contreras A

J Dairy Sci 106:3650-3661.
2023

NO RESULTS

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