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Publications

Our research is regularly featured in leading scientific journals across the fields of metabolism, pharmacology, cannabinoid science, and translational medicine. These publications reflect our lab’s commitment to advancing fundamental knowledge and developing innovative therapeutic strategies with real-world impact.

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Hyperactivation of Anandamide Synthesis and Regulation of Cell-cycle Progression via Cannabinoid Type 1 (CB1) Receptors in the Regenerating Liver

Mukhopadhyay B, Cinar R, Yin S, Liu J, Tam J, Godlewski G, Harvey-White J, Mordi I, Cravatt BF, Lotersztajn S, Gao B, Yuan Q, Schuebel K, Goldman D, Kunos G

Proc Natl Acad Sci USA 108:6323-6328.
2011

Highlighted in Proc Natl Acad Sci USA (2011) 108: 6339-40.

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Endocannabinoids in Liver Disease

Tam J, Liu J, Mukhopadhyay B, Cinar R, Godlewski G, Kunos G

Hepatology 53:346-355.
2011
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Inhibitor of Fatty Acid Amide Hydrolase Normalizes Cardiovascular Function in Hypertension without Adverse Metabolic Effects

Godlewski G, Alapafuja SO, Bátkai S, Nikas SP, Cinar R, Offertáler L, Osei-Hyiaman D, Liu J, Mukhopadhyay B, Harvey-White J, Tam J, Pacak K, Cravatt BF, Makriyannis A,  Kunos G

Chem Biol 17:1256–1266.
2010
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Peripheral CB1 Cannabinoid Receptor Blockade Improves Cardiometabolic Risk in Mouse Models of Obesity

Tam J, Vemuri VK, Liu J, Bátkai C, Mukhopadhyay B, Godlewski G, Osei-Hyiaman D, Ohnuma S, Ambudkar SV, Makriyannis A, Kunos G

J Clin Invest 120:2953–2966.
2010

Highlighted in J Clin Invest (2010) 120:2646-8.

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Oleoyl-serine, an Endogenous N-acyl Amide Modulates Bone Remodeling and Mass

Smoum R, Bar A, Tan B, Milman G, Attar-Namdar M, Ofek O, Stuart JM, Bajayo A, Tam J, Kram V, O’Dell D, Walker MJ, Bradshaw HB, Bab I, Mechoulam R

Proc Natl Acad Sci USA 107:17710-17715.
2010
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Lef1 Haploinsufficient Mice Display a Low Turnover and Low Bone Mass Phenotype in a Gender- and Age-Specific Manner

Noh T, Gabet Y, Cogan J, Shi Y, Tank A, Sasaki T, Criswell B, Dixon A,  Lee C, Tam J, Kohler T, Segev E, Kockeritz L, Woodgett J, Müller R, Chai Y, Smith E, Bab I, Frenkel B

PLoS One 4:e5438.​​
2009
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Endocannabinoids and the Regulation of Bone Metabolism

Bab I, Ofek O, Tam J, Rehnelt J, Zimmer A

J Neuroendocrinol 20 Suppl 1:69-74.
2008
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The Cannabinoid CB1 Receptor Regulates Bone Formation by Modulating Adrenergic Signaling

Tam J, Trembovler V, Di Marzo V, Petrosino S, Leo G, Alexandrovich A, Regev E, Casap N, Shteyer, A, Ledent C, Karsak M, Zimmer A, Mechoulam R, Yirmiya R, Shohami E, Bab I

FASEB J 22:285-294.
2008
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Involvement of Neuronal Cannabinoid Receptor, CB1, in Regulation of Bone mass and Bone Remodeling

Tam J, Ofek O, Fride E, Ledent C, Gabet Y, Müller R, Zimmer A, Mackie K, Mechoulam R, Shohami E, Bab I

Mol Pharmacol 70:786-792.
2006
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Peripheral CB2 Cannabinoid Receptor Regulates Bone Mass

Ofek O, Karsak M, Leclerc N, Fogel M, Frenkel B, Wright K, Tam J, Attar-Namdar M, Kram V, Shohami E, Mechoulam R, Zimmer A, Bab I

Proc Natl Acad Sci USA 103:696-701.
2006

NO RESULTS

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